Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly

sarcopenic men: a randomised controlled trial

The influence of protein supplementation with collagen and resistance training on muscle mass and muscle function in elderly sarcopenic subjects.

JUNE 29, 2015

Written by Denise Zdzieblik, Steffen Oesser, Manfred W. Baumstark, Albert Gollhofer, Daniel König

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Protein supplementation in combination with resistance training may increase muscle mass and muscle strength in elderly subjects. The objective of this study was to assess the influence of post-exercise protein supplementation with collagen peptides v. placebo on muscle mass and muscle function following resistance training in elderly subjects with sarcopenia. A total of fifty-three male subjects (72·2 (SD 4·68) years) with sarcopenia (class I or II) completed this randomised double-blind placebo-controlled study. All the participants underwent a 12-week guided resistance training programme (three sessions per week) and were supplemented with either collagen peptides (treatment group (TG)) (15 g/d) or silica as placebo (placebo group (PG)). Fat-free mass (FFM), fat mass (FM) and bone mass (BM) were measured before and after the intervention using dual-energy X-ray absorptiometry. Isokinetic quadriceps strength (IQS) of the right leg was determined and sensory motor control (SMC) was investigated by a standardised one-leg stabilisation test. Following the training programme, all the subjects showed significantly higher (P<0·01) levels for FFM, BM, IQS and SMC with significantly lower (P <0·01) levels for FM. The effect was significantly

more pronounced in subjects receiving collagen peptides: FFM (TG +4·2 (SD 2·31) kg/PG +2·9 (SD 1·84) kg; P <0·05); IQS (TG +16·5 (SD 12·9) Nm/PG +7·3 (SD 13·2) Nm; P<0·05); and FM (TG –5·4 (SD 3·17) kg/PG –3·5 (SD 2·16) kg; P< 0·05). Our data demonstrate that compared with placebo, collagen peptide supplementation in combination with resistance training further improved body composition by increasing FFM, muscle strength and the loss in FM.



In conclusion, the findings of the present study have confirmed previous results that 60 min of resistance exercise, performed three times per week, is well suited to significantly increase muscle mass, muscular strength and motor control in subjects with sarcopenia class I or II. Moreover, the study has demonstrated that the combination of resistance exercise and collagen peptide supplementation resulted in a more pronounced improvement of body composition, as indicated by a significant increase in muscle mass and decrease in FM, compared with placebo. In addition, muscular strength was significantly improved after collagen peptide intake compared with the training programme plus placebo.