Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults: A pilot study
The effects of 8-h time restricted feeding on body weight and metabolic disease risk factors in obese adults.
Time restricted feeding decreases energy intake without calorie counting and may be a viable option for weight loss. However, the effect of this diet on body weight in obese subjects has never been examined. This study investigated the effects of 8-h time restricted feeding on body weight and metabolic disease risk factors in obese adults. Obese subjects (n = 23) participated in an 8-h time restricted feeding intervention (ad libitum feeding between 10:00 to 18:00 h, water fasting between 18:00 to 10:00 h) for 12 weeks. Weight loss and other outcomes were compared to a matched historical control group (n = 23). Body weight and energy intake decreased in the time restricted group (–2.6% ± 0.5; –341 ± 53 kcal/d) relative to controls over 12 weeks (P < 0.05). Systolic blood pressure decreased in the time restricted feeding group (–7 ± 2 mm Hg) versus controls (P < 0.05). Fat mass, lean mass, visceral fat mass, diastolic blood pressure, LDL cholesterol, HDL cholesterol, triglycerides, fasting glucose, fasting insulin, HOMA-IR, and homocysteine were not significantly different from controls after 12 weeks (no group×time interaction). These findings suggest that 8-h time restricted feeding produces mild caloric restriction and weight loss, without calorie counting. It may also offer clinical benefits by reducing blood pressure.
In summary, these findings suggest that 8-h time restricted feeding produces mild caloric restriction and weight loss in obese adults, without intentional calorie counting. This diet may also offer some clinical benefit by reducing systolic blood pressure. These preliminary data offer promise for the use of time restricted feeding as a weight loss technique in obese adults, but longer-term, larger-scale randomized controlled trials will be required before solid conclusions can be reached.